Effects of Etoricoxib on Sevoflurane Requirement in Ankle Surgery
Author Information
Author(s): Turan Ibrahim, Hein Anette, Jacobson Eva, Jakobsson Jan G
Primary Institution: Karolinska Institutet
Hypothesis
Does preoperative administration of etoricoxib reduce the need for sevoflurane during elective ankle surgery?
Conclusion
Coxib premedication before elective day surgery has an anaesthetic sparing potential.
Supporting Evidence
- The mean end-tidal sevoflurane concentration was significantly lower in the preoperative group.
- No complications or adverse events were reported during the study.
- Emergence and recovery times were similar between both groups.
Takeaway
Giving a medicine called etoricoxib before ankle surgery can help use less of the sleepy medicine sevoflurane.
Methodology
A prospective randomized study comparing sevoflurane requirements in patients receiving etoricoxib preoperatively versus postoperatively.
Potential Biases
Potential bias due to non-blinded study design.
Limitations
The study design is not double-blinded and the number of patients was limited.
Participant Demographics
44 patients, 17 males and 27 females, mean age 45 years.
Statistical Information
P-Value
<0.0001
Statistical Significance
p<0.0001
Digital Object Identifier (DOI)
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