The PIC Cystogram: A New Test for Recurrent Febrile UTIs
Author Information
Author(s): Jennifer A. Hagerty, Max Maizels, Earl Y. Cheng
Primary Institution: Children's Memorial Hospital
Hypothesis
Can the PIC cystogram identify occult vesicoureteral reflux in children with recurrent febrile UTIs who have normal VCUG results?
Conclusion
The PIC cystogram can identify clinically significant occult VUR, and treating this condition significantly reduces the incidence of recurrent febrile UTIs.
Supporting Evidence
- The PIC cystogram identified occult VUR in 82% of patients with recurrent febrile UTIs and negative VCUGs.
- Treatment of VUR identified by PIC cystography significantly reduced the incidence of febrile UTIs from 0.16 to 0.008 per case per month.
- All patients treated for PIC-VUR did not experience recurrent febrile UTIs during follow-up.
Takeaway
The PIC cystogram is a special test that helps find hidden problems in kids with repeated urinary infections, and fixing these problems can help them feel better.
Methodology
The literature was searched to evaluate studies on PIC cystography, and data from multiple studies were analyzed.
Potential Biases
Potential bias may arise from the selection of patients and the interpretation of results.
Limitations
Current literature on PIC cystography is limited, and further studies are needed to confirm its efficacy.
Participant Demographics
Children with recurrent febrile UTIs and normal VCUG results.
Statistical Information
P-Value
0.008
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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