Molecular Epidemiology of Hepatitis B Virus in India
Author Information
Author(s): Datta Sibnarayan
Primary Institution: ICMR Virus Unit Kolkata
Hypothesis
What are the distinct molecular epidemiological patterns of hepatitis B virus (HBV) in different regions of India?
Conclusion
The study reveals that eastern India has a unique distribution of HBV genotypes, including A, C, and D, which influences disease severity and transmission patterns.
Supporting Evidence
- HBV genotypes A and D are prevalent in mainland India, while genotype C is found in eastern India.
- The study indicates that genotype C may have been recently introduced to eastern India.
- High rates of HBV infection are reported among certain tribes in the Andaman and Nicobar Islands.
Takeaway
This study looks at how different types of the hepatitis B virus are spread in India, especially in the east, and how they can make people sick in different ways.
Methodology
The study involved analyzing HBV genotypes and their clinical significance among different populations in India.
Limitations
Data on HBV molecular epidemiology in India is limited, and the study primarily focuses on eastern India.
Participant Demographics
The study included a diverse population from various regions of India, particularly focusing on eastern India and certain tribes.
Digital Object Identifier (DOI)
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