BODY AND MIND: EXPLORING ASSOCIATIONS AMONG PARALLEL TRAJECTORIES OF BIOMARKERS AND DEPRESSION SCORES
2024

Associations Between Biomarkers and Depression Scores

publication Evidence: moderate

Author Information

Author(s): Brian Beach, Paola Zaninotto, Eun-Jung Shim

Primary Institution: University College London

Hypothesis

This study examines whether associations exist between the trajectories of biomarkers and depression scores.

Conclusion

The study found that while there are associations between blood hemoglobin and depression, other biomarkers showed no significant associations.

Supporting Evidence

  • Associations were found between blood hemoglobin and depression scores.
  • Men showed a negative association between depression and HDL cholesterol.
  • The study used data collected during nurse visits between 2004 and 2019.

Takeaway

The study looked at how certain blood tests relate to feelings of sadness in older people, but only one test showed a connection.

Methodology

The study used data from the English Longitudinal Study of Ageing, analyzing four measurement points for depression and nine biomarkers among respondents aged 50+.

Limitations

The study cannot demonstrate a causal relationship between biomarkers and depression.

Participant Demographics

Respondents aged 50+ from the English Longitudinal Study of Ageing.

Statistical Information

Confidence Interval

95%CI: 0.004,0.054

Digital Object Identifier (DOI)

10.1093/geroni/igae098.0926

Want to read the original?

Access the complete publication on the publisher's website

View Original Publication