Semiquantitative assessment of subchondral bone marrow edema-like lesions and subchondral cysts of the knee at 3T MRI: A comparison between intermediate-weighted fat-suppressed spin echo and Dual Echo Steady State sequences
2011

Comparing MRI Techniques for Knee Lesions

Sample size: 201 publication Evidence: high

Author Information

Author(s): Hayashi Daichi, Guermazi Ali, Kwoh C Kent, Hannon Michael J, Moore Carolyn, Jakicic John M, Green Stephanie M, Roemer Frank W

Primary Institution: Boston University School of Medicine

Hypothesis

The study aims to compare the effectiveness of two MRI sequences in assessing subchondral bone marrow edema-like lesions and subchondral cysts in the knee.

Conclusion

The intermediate-weighted fat-suppressed sequence is better at depicting subchondral bone marrow edema-like lesions, while the DESS sequence is more effective for subchondral cysts.

Supporting Evidence

  • The IW fs sequence detected 93 lesions (46.5%) that were not seen on the DESS sequence.
  • The IW fs sequence showed larger sizes of subchondral BMLs in 93% of cases compared to DESS.
  • DESS demonstrated larger subchondral cysts in 36.4% of cases compared to IW fs.

Takeaway

This study looked at two types of MRI scans to see which one shows knee problems better. One scan is better for seeing certain types of swelling, while the other is better for seeing cysts.

Methodology

201 subjects aged 35-65 with frequent knee pain underwent 3T MRI using both IW fs and DESS sequences, with assessments made according to the WORMS system.

Limitations

The study lacks a definitive reference standard for the true size of subchondral BMLs and only involves a cross-sectional analysis.

Participant Demographics

Mean age was 52.3 years, with slightly more men (53.7%) than women, and participants were generally overweight (mean BMI 29.1).

Statistical Information

P-Value

p < 0.0001

Statistical Significance

p < 0.0001

Digital Object Identifier (DOI)

10.1186/1471-2474-12-198

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