Minimally invasive surgery versus open gastrectomy for older patients with gastric cancer: A propensity score‐matching analysis
2025

Minimally Invasive Surgery vs. Open Gastrectomy for Older Patients with Gastric Cancer

Sample size: 332 publication 10 minutes Evidence: moderate

Author Information

Author(s): Yamamoto Masaaki, Omori Takeshi, Masuike Yasunori, Shinno Naoki, Hara Hisashi, Sugase Takahito, Kanemura Takashi, Takeno Atsushi, Hirao Motohiro, Miyata Hiroshi

Primary Institution: Osaka International Cancer Institute

Hypothesis

Is minimally invasive surgery more beneficial than open surgery for older patients with gastric cancer?

Conclusion

Minimally invasive surgery for older patients with gastric cancer may be more beneficial than open gastrectomy in terms of blood loss and hospital stay.

Supporting Evidence

  • The laparoscopy group had a longer operative time but less blood loss and shorter hospital stays than the open surgery group.
  • The complication rate was lower in the laparoscopy group compared to the open surgery group.
  • No significant differences were noted in overall, recurrence-free, and disease-free survival between the groups.

Takeaway

This study found that older patients with gastric cancer might recover better with minimally invasive surgery than with traditional open surgery.

Methodology

The study included 464 patients aged 75 and older who underwent either open or laparoscopic gastrectomy, with outcomes compared after propensity score matching.

Potential Biases

Potential biases could not be completely eliminated despite propensity score matching.

Limitations

The study was retrospective, conducted at a single institution, and had a relatively small sample size.

Participant Demographics

Patients aged 75 years and older with gastric cancer.

Statistical Information

P-Value

p<0.020

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1002/ags3.12842

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