Resistive Exercise for Arthritic Cartilage Health (REACH): A randomized double-blind, sham-exercise controlled trial
2009

Resistive Exercise for Arthritic Cartilage Health (REACH): A Study on Knee Osteoarthritis

Sample size: 63 publication Evidence: moderate

Author Information

Author(s): Angela K Lange, Benedicte Vanwanseele, Nasim Foroughi, Michael K Baker, Ronald Shnier, Richard M Smith, Maria A Fiatarone Singh

Primary Institution: University of Sydney

Hypothesis

High intensity progressive resistance training will decelerate cartilage degeneration in women with knee osteoarthritis.

Conclusion

The study aims to evaluate the effectiveness of progressive resistance training in improving cartilage health in women with knee osteoarthritis.

Supporting Evidence

  • Progressive resistance training has been shown to improve pain and disability in osteoarthritic populations.
  • The study is the first to assess the disease-modifying potential of resistance training on cartilage health.
  • Participants were randomized to ensure unbiased results.
  • Blinded MRI measurements were used to assess cartilage morphology.

Takeaway

This study is trying to see if lifting weights can help women with bad knees feel better and keep their knees from getting worse.

Methodology

Women over 40 with knee osteoarthritis were randomly assigned to either a resistance training group or a sham-exercise group for 6 months, with outcomes measured via MRI and various physical performance tests.

Potential Biases

Potential biases may arise from the self-reported nature of some outcomes and the blinding process.

Limitations

The study may have limitations related to participant dropout and the generalizability of results to other populations.

Participant Demographics

Women over 40 years of age with primary knee osteoarthritis.

Statistical Information

P-Value

0.043

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1186/1471-2318-9-1

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