Nifedipine-Induced Gingival Overgrowth in Brazilian Patients
Author Information
Author(s): Cliciane Portela Sousa, Claudia Maria Navarro, Maria Regina Sposto
Primary Institution: Department of Diagnosis and Oral Surgery, Dental School, UNESP, Brazil
Hypothesis
What is the prevalence and severity of nifedipine-induced gingival overgrowth in Brazilian patients?
Conclusion
The study found that gingival inflammation is the main risk factor for nifedipine-induced gingival overgrowth.
Supporting Evidence
- 68% of patients taking nifedipine showed gingival overgrowth compared to 23% in the control group.
- The Clinical Index DIGO was effective in evaluating gingival overgrowth.
- Inflammation of the gums was strongly associated with the severity of gingival overgrowth.
Takeaway
This study looked at how a medicine called nifedipine can make gums grow too much in people. It found that having inflamed gums is a big reason why this happens.
Methodology
The study involved 35 patients taking nifedipine and 35 control patients, assessing various demographic, pharmacological, and periodontal variables.
Potential Biases
Potential bias in patient selection and self-reported data.
Limitations
The study may not represent all Brazilian patients due to the specific selection criteria.
Participant Demographics
The test group had a mean age of 69.5 years, with a higher prevalence of males.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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