Interstitial Pneumonitis After Chemotherapy
Author Information
Author(s): Zappa Luis, Savady Renaldo, Humphries Gary N, Sugarbaker Paul H
Primary Institution: Washington Cancer Institute, Washington, DC, USA
Hypothesis
Can intrapleural chemotherapy cause interstitial pneumonitis and lung fibrosis?
Conclusion
This case report is the first to describe interstitial pneumonitis and lung fibrosis following intrapleural chemotherapy, suggesting that dose reduction may be necessary.
Supporting Evidence
- Chemotherapy can affect lung function, but the extent of damage from intrapleural chemotherapy is unclear.
- Prior cases of chemotherapy-induced lung damage have been documented, but this specific case is unique.
- Mitomycin C has been associated with lung toxicity in other studies, indicating a potential risk.
Takeaway
One patient got really sick with lung problems after receiving special chemotherapy in their chest, and it didn't get better.
Methodology
Case report detailing the patient's treatment and subsequent health issues.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
A 48-year-old woman with appendiceal mucinous neoplasm.
Digital Object Identifier (DOI)
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