Farmed Salmon and Insulin Resistance in Mice
Author Information
Author(s): Ibrahim Mohammad Madani, Fjære Even, Lock Erik-Jan, Naville Danielle, Amlund Heidi, Meugnier Emmanuelle, Le Magueresse Battistoni Brigitte, Frøyland Livar, Madsen Lise, Jessen Niels, Lund Sten, Vidal Hubert, Ruzzin Jérôme
Primary Institution: National Institute of Nutrition and Seafood Research, Bergen, Norway
Hypothesis
Does a diet containing farmed salmon contribute to insulin resistance in mice?
Conclusion
Intake of farmed salmon fillet contributes to insulin resistance and obesity in mice, partly due to persistent organic pollutants (POPs).
Supporting Evidence
- Mice fed farmed salmon gained more weight than those on other diets.
- Consumption of farmed salmon increased visceral fat and insulin resistance.
- Mice on a diet with reduced POPs showed less weight gain and better insulin sensitivity.
Takeaway
Eating farmed salmon can make mice gain weight and have trouble with insulin, which is not good for their health.
Methodology
Mice were fed different diets including farmed salmon and assessed for body weight, fat mass, insulin sensitivity, and glucose tolerance.
Potential Biases
Potential bias in dietary intake assessment and environmental pollutant exposure.
Limitations
The study was conducted on mice, which may not fully represent human responses.
Participant Demographics
Adult male C57BL/6J mice.
Statistical Information
P-Value
p<0.05
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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