Developmental Patterns of Auditory Responses in Children
Author Information
Author(s): Kotecha Rupesh, Pardos Maria, Wang Yingying, Wu Ting, Horn Paul, Brown David, Rose Douglas, deGrauw Ton, Xiang Jing
Primary Institution: Cincinnati Children's Hospital Medical Center
Hypothesis
A comprehensive analysis of M50, M70, and M100 would reveal at least one component that changes significantly with age.
Conclusion
The study found clear developmental patterns in the auditory cortex of children, with M70 being a key indicator of auditory development.
Supporting Evidence
- The latency of M70 in the right hemisphere highly correlated to the age of the child.
- The amplitudes of the M70 responses increased with age and peaked in children aged 12-14 years.
- The study identified three main responses at approximately 46 ms (M50), 71 ms (M70), and 106 ms (M100) in latency for children.
Takeaway
This study looked at how children's brains respond to sounds as they grow up, finding that certain responses change with age.
Methodology
The study used a 275-channel MEG system to measure auditory responses in 60 children and 20 adults.
Limitations
The study focused primarily on children aged 6-17 and did not analyze later responses beyond M100.
Participant Demographics
60 healthy children aged 6-17 years (30 female, 30 male) and 20 healthy adults aged 19-49 years (10 female, 10 male).
Statistical Information
P-Value
p<0.001
Statistical Significance
p<0.001
Digital Object Identifier (DOI)
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