Effect of integration of supplemental nutrition with public health programmes in pregnancy and early childhood on cardiovascular risk in rural Indian adolescents: long term follow-up of Hyderabad nutrition trial
2008

Nutrition and Cardiovascular Risk in Indian Adolescents

Sample size: 1165 publication Evidence: high

Author Information

Author(s): Sanjay Kinra, Rameshwar Sarma K V, Ghafoorunissa, Mendu Vishnu Vardhana Rao, Ravikumar Radhakrishnan, Mohan Viswanthan, Ian B Wilkinson, John R Cockcroft, George Davey Smith, Yoav Ben-Shlomo

Primary Institution: London School of Hygiene and Tropical Medicine

Hypothesis

Does integrating nutritional supplementation with public health programs in early life reduce cardiovascular disease risk in undernourished populations?

Conclusion

The study found that integrated nutritional supplementation in early life was associated with a more favorable cardiovascular risk profile in adolescents.

Supporting Evidence

  • Participants from intervention villages were 14 mm taller than controls.
  • Lower insulin resistance and arterial stiffness were observed in the intervention group.
  • No strong evidence for differences in blood pressures and serum lipids.

Takeaway

Giving better food to pregnant women and young kids can help kids grow taller and be healthier when they are teenagers.

Methodology

The study followed participants from a previous trial, comparing those who received nutritional supplementation with those who did not, measuring various health outcomes.

Potential Biases

Non-randomization and loss to follow-up may introduce bias in the results.

Limitations

Potential bias due to non-randomization of villages and losses to follow-up.

Participant Demographics

Adolescents aged 13-18 years from 29 villages in rural India.

Statistical Information

P-Value

P=0.007

Confidence Interval

95% confidence interval 4 to 23

Statistical Significance

p<0.05

Digital Object Identifier (DOI)

10.1136/bmj.a605

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