Using qualitative synthesis to explore heterogeneity of complex interventions
2011

Exploring Patient Perspectives in HIV Treatment Adherence

Sample size: 916 publication 10 minutes Evidence: moderate

Author Information

Author(s): Candy Bridget, King Michael, Jones Louise, Oliver Sandy

Primary Institution: University College London

Hypothesis

Can integrating qualitative evidence on patients' perspectives improve understanding of adherence to HIV treatment?

Conclusion

The study found that effective interventions for HIV treatment adherence often align more closely with patients' concerns.

Supporting Evidence

  • Effective interventions contained a broader range of components that addressed barriers to adherence.
  • Interventions that matched patient recommendations were more likely to improve adherence.
  • Qualitative evidence can provide insights into why some interventions are more effective than others.

Takeaway

This study looked at how patients feel about their HIV treatment and found that when treatments match what patients care about, they are more likely to stick to them.

Methodology

The study used a matrix to compare qualitative evidence from patient perspectives with data from a Cochrane review on HIV treatment adherence.

Potential Biases

There is a risk of bias due to incomplete reporting in trial reports and subjective evaluation of matches between qualitative and quantitative data.

Limitations

The conclusions drawn are tentative due to the methodological weaknesses of the trials included.

Participant Demographics

Participants were HIV/AIDS patients, with a total sample size of 916 from the qualitative review.

Digital Object Identifier (DOI)

10.1186/1471-2288-11-124

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