Low-Density Scalp Electrical Source Imaging in Pediatric Epilepsy Surgery
Author Information
Author(s): Sadeghzadeh Parnia, Freibauer Alexander, RamachandranNair Rajesh, Whitney Robyn, Al Nassar Mutaz, Jain Puneet, Donner Elizabeth, Ochi Ayako, Jones Kevin C.
Primary Institution: McMaster Children’s Hospital, Hamilton, ON, Canada
Hypothesis
Can low-density scalp electrical source imaging effectively localize the ictal onset zone and interictal spike ripple networks in children undergoing epilepsy surgery?
Conclusion
The study suggests that low-density scalp electrical source imaging can be a promising non-invasive technique for localizing the ictal onset zone and spike ripple networks in pediatric epilepsy surgery.
Supporting Evidence
- Six of seven patients with ictal source coherence maps included the surgical resection.
- Five of seven patients were seizure-free post-resection.
- Three patients underwent interictal spike ripple electrical source imaging, with all being seizure-free.
Takeaway
This study shows that a special brain scan can help doctors find the exact spot in the brain that causes seizures in kids, which can help them do surgery to stop the seizures.
Methodology
A retrospective review of 12 pediatric patients who underwent focal resections, using source coherence maps generated from scalp EEG data.
Limitations
The study is limited by its small sample size and retrospective design, which may affect the generalizability of the findings.
Participant Demographics
Median age of participants was 11 years, with 7 females and 5 males.
Digital Object Identifier (DOI)
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