Osteosarcoma of the Urinary Bladder in a Patient with Lupus
Author Information
Author(s): Baydar Dilek Ertoy, Himmetoglu Cigdem, Yazici Sertac, Kiziloz Halil, Ozen Haluk
Primary Institution: Hacettepe University Hospital
Hypothesis
Is there a link between systemic lupus erythematosus and the development of osteosarcoma in the urinary bladder?
Conclusion
Long-term immunosuppressive therapy and systemic lupus erythematosus may contribute to the development of primary osteosarcoma in the urinary bladder.
Supporting Evidence
- Only 30 cases of primary osteosarcoma of the urinary bladder have been reported in the literature.
- The patient had a long history of systemic lupus erythematosus and was treated with immunosuppressive agents.
- Malignant neoplasms occur more commonly in patients with systemic lupus erythematosus than in the general population.
Takeaway
A 24-year-old woman with lupus developed a rare type of cancer in her bladder after many years of treatment. This shows that some medicines for lupus might increase cancer risk.
Methodology
Case report detailing the patient's medical history, diagnosis, and treatment.
Potential Biases
Potential bias due to the unique nature of the case and lack of broader data.
Limitations
Only one case is reported, limiting generalizability.
Participant Demographics
24-year-old Caucasian woman with a 13-year history of systemic lupus erythematosus.
Digital Object Identifier (DOI)
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