Dynamic evolution of bitter taste receptor genes in vertebrates
2009
Evolution of Bitter Taste Receptor Genes in Vertebrates
publication
Evidence: moderate
Author Information
Author(s): Dong Dong, Gareth Jones, Shuyi Zhang
Primary Institution: East China Normal University
Hypothesis
How do bitter taste receptor (T2R) genes evolve in vertebrates?
Conclusion
The study shows that T2R gene repertoires are closely related to dietary habits and that their evolution is influenced by birth-and-death processes.
Supporting Evidence
- T2R gene repertoires vary significantly among vertebrate species.
- Teleost fishes have more diverse T2R gene families compared to tetrapods.
- Independent gene expansions were observed in frogs, mammals, and lizards.
Takeaway
This study looks at how different animals have evolved their ability to taste bitterness, which helps them avoid harmful foods.
Methodology
The study identified T2R gene repertoires from high coverage genome sequences and analyzed evolutionary changes using the reconciled-tree method.
Limitations
Some genome sequences were incomplete, which may lead to underestimation of T2R gene numbers.
Digital Object Identifier (DOI)
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