Pregnancy outcome in women before and after cervical conisation: population based cohort study

2008

Pregnancy Outcomes After Cervical Conisation

Sample size: 15108 publication Evidence: high

Author Information

Author(s): Susanne Albrechtsen, Svein Rasmussen, Steinar Thoresen, Lorentz M. Irgens, Ole Erik Iversen

Primary Institution: Haukeland University Hospital, University of Bergen

What are the consequences of cervical conisation on subsequent pregnancy outcomes?

Cervical conisation increases the risk of preterm delivery, especially in early gestational age groups.

The proportion of preterm delivery was 17.2% in women who gave birth after cervical conisation.
The relative risk of late abortion was 4.0 in women who gave birth after cervical conisation compared to those who did not.
The risk of preterm delivery declined during the study period.

Women who have had a cervical conisation might have babies earlier than expected, which can be risky.

Population based cohort study using data from the Cancer Registry of Norway and the Medical Birth Registry of Norway.

Misclassification of exposure could occur, but it would not significantly influence the relative risks.

Potential confounding factors such as smoking were not accounted for in the registries.

Women aged less than 45 at the time of cervical conisation.

95% confidence interval 3.3 to 4.8

p<0.05

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