Diversity of Actinomyces naeslundii and Actinomyces oris
Author Information
Author(s): Henssge Uta, Do Thuy, Gilbert Steven C., Cox Steven, Clark Douglas, Wickström Claes, Ligtenberg A. J. M., Radford David R., Beighton David
Primary Institution: King's College London Dental Institute
Hypothesis
How do the population structures of Actinomyces naeslundii and Actinomyces oris differ?
Conclusion
The study reveals significant genotypic and phenotypic diversity within Actinomyces naeslundii and Actinomyces oris.
Supporting Evidence
- A. oris is more abundant and frequently isolated than A. naeslundii.
- 32 unique sequence types were identified for A. naeslundii and 68 for A. oris.
- At least 4 significant subclusters were identified within A. oris.
Takeaway
This study looked at two types of bacteria in our mouths and found that they are very different from each other in many ways.
Methodology
Multi-locus sequence typing (MLST) and analysis of partial fimA and fimP gene sequences were used to investigate the diversity of the two species.
Limitations
The strain collection investigated may not represent the total population of these species.
Digital Object Identifier (DOI)
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