CLINICAL TRIALS OF GEROTHERAPEUTICS FOR TARGETING LOWER URINARY TRACT SYMPTOMS
2024
Targeting Aging to Help Bladder Issues in Older Women
publication
Author Information
Author(s): Al-Naggar Iman
Primary Institution: UConn Health, Farmington, Connecticut, United States
Hypothesis
Can targeting biological hallmarks of aging alleviate lower urinary tract symptoms in older women?
Conclusion
Targeting biological mechanisms of aging may lead to more effective treatments for lower urinary tract symptoms in older women.
Supporting Evidence
- Aging and metabolic syndrome are risk factors for lower urinary tract symptoms.
- Dysregulated mechanisms along the brain-to-bladder pathway can lead to these symptoms.
- Current treatments like anticholinergics often fail due to side effects.
- Identifying novel targets could lead to better drug development.
Takeaway
As people get older, they can have more problems with their bladder. This study is looking at ways to help fix those problems by focusing on aging.
Methodology
The study involves pilot and feasibility studies using repurposed drugs or supplements to target aging mechanisms.
Participant Demographics
Older women
Digital Object Identifier (DOI)
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