Effects of Staphylococcus aureus on Cow Milk and Serum Proteins
Author Information
Author(s): Kim Yunee, Atalla Heba, Mallard Bonnie, Robert Claude, Karrow Niel
Primary Institution: University of Guelph
Hypothesis
The host immune response will be different for small colony variant (SCV) strains of Staphylococcus aureus compared to typical strains.
Conclusion
Different strains of Staphylococcus aureus cause varying immune protein responses in dairy cattle during intramammary infections.
Supporting Evidence
- Serum IL-8, IFN-γ, and TGF-β1 responses differed in dairy cows challenged with different strains of S. aureus.
- Unique host protein expression profiles were observed that depended on the infecting strain.
- CPP3 was differentially expressed between the S. aureus treatment groups.
Takeaway
When cows get infected with different types of bacteria, their bodies react in different ways, which can affect their milk.
Methodology
The study monitored immune protein responses in serum and milk after intramammary infection with three strains of Staphylococcus aureus over a 21-day period.
Limitations
The study did not include later time points to assess ongoing immune responses.
Participant Demographics
Healthy Holstein dairy cows in mid-to-late lactation.
Statistical Information
P-Value
p<0.01
Statistical Significance
p<0.05
Digital Object Identifier (DOI)
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