AGE RELATED CHANGES IN THE MICROBIOME AND THEIR IMPACT ON DISEASE
2024
Impact of Aging on the Gut Microbiome and Disease
publication
Author Information
Author(s): Louise McCullough
Primary Institution: McGovern Medical School at UTHealth, Houston, Texas, United States
Hypothesis
How do age-related changes in the microbiome affect disease?
Conclusion
The study suggests that changes in the gut microbiota with aging may contribute to neurological diseases and that targeting these changes could have therapeutic potential.
Supporting Evidence
- The gut microbiota plays a critical role in regulating host immunity and metabolism.
- Disruption in gut microbial communities can lead to inflammation in the gut and brain.
- Preclinical studies show that therapies targeting gut microbiota can improve behavioral outcomes.
Takeaway
As we get older, the tiny bugs in our gut change, which can make us sick, but fixing these changes might help us feel better.
Digital Object Identifier (DOI)
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