Feasibility Study of a Diet and Cancer Cohort in India
Author Information
Author(s): Sinha Rashmi, Daniel Carrie R, Devasenapathy Niveditha, Shetty Hemali, Yurgalevitch Susan, Ferrucci Leah M, George Preethi S, Morrissey Kerry Grace, Ramakrishnan Lakshmy, Graubard Barry I, Kapur Kavita, Reddy K Srinath, McAdams Mary J, Rastogi Tanuja, Chatterjee Nilanjan, Gupta Prakash C, Wacholder Sholom, Prabhakaran Dorairaj, Mathew Aleyamma A
Primary Institution: National Cancer Institute, National Institutes of Health, Department of Health and Human Services, Rockville, MD, USA
Hypothesis
Can a diet-focused cohort study of cancer be established in India to provide insights into unique dietary and lifestyle exposures?
Conclusion
The study found that a high percentage of participants complied with study procedures, indicating the feasibility of conducting a population-based study in India.
Supporting Evidence
- 88% of eligible subjects completed all questionnaires.
- 67% provided biological samples.
- Unique protein sources varied by region: fish in Trivandrum, dairy in New Delhi, and pulses in Mumbai.
- A large percentage of participants were centrally obese and had elevated blood glucose levels.
- New Delhi participants were the least physically active and had elevated lipid levels.
Takeaway
Researchers wanted to see if they could study how diet affects cancer in India, and they found that many people were willing to help with the study.
Methodology
Field staff contacted 7,064 households and collected data through questionnaires and biological samples from eligible adults aged 35-69 years.
Potential Biases
Recruitment was restricted to individuals willing to provide biological samples, which may introduce bias.
Limitations
Challenges included limited facilities for biological sample handling and potential recruitment bias.
Participant Demographics
Participants were aged 35-69 years, with a diverse representation from different regions, religions, and socio-economic backgrounds.
Digital Object Identifier (DOI)
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