An ex vivo, assessor blind, randomised, parallel group, comparative efficacy trial of the ovicidal activity of three pediculicides after a single application - melaleuca oil and lavender oil, eucalyptus oil and lemon tea tree oil, and a 'suffocation' pediculicide
2011

Effectiveness of Different Pediculicides Against Head Lice Eggs

Sample size: 92 publication 10 minutes Evidence: high

Author Information

Author(s): Stephen C Barker, Phillip M Altman

Primary Institution: University of Queensland

Hypothesis

How effective are different pediculicides at killing head lice eggs?

Conclusion

The 'suffocation' pediculicide and melaleuca oil and lavender oil pediculicide were significantly more effective at killing head lice eggs than eucalyptus oil and lemon tea tree oil.

Supporting Evidence

  • The 'suffocation' pediculicide had an ovicidal efficacy of 68.3%.
  • Melaleuca oil and lavender oil pediculicide had an ovicidal efficacy of 44.4%.
  • Eucalyptus oil and lemon tea tree oil pediculicide had an ovicidal efficacy of 3.3%.
  • The study involved 92 subjects who were randomly assigned to treatment groups.

Takeaway

Some lice treatments work much better than others at killing the eggs. The best ones can kill over 68% of the eggs!

Methodology

This was an assessor-blind, randomised, parallel group, comparative study involving subjects with live head lice eggs.

Potential Biases

Potential bias due to the non-blinding of the treatment applicator.

Limitations

The study was limited to a specific population and may not generalize to all demographics.

Participant Demographics

Elementary school-aged children (aged 4 to 12 years) from Queensland, Australia.

Statistical Information

P-Value

<0.0001

Statistical Significance

p<0.0001

Digital Object Identifier (DOI)

10.1186/1471-5945-11-14

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