A Rice Gene of De Novo Origin Negatively Regulates Pathogen-Induced Defense Response
2009

A New Rice Gene Regulates Defense Against Pathogens

Sample size: 23 publication 10 minutes Evidence: high

Author Information

Author(s): Xiao Wenfei, Liu Hongbo, Li Yu, Li Xianghua, Xu Caiguo, Long Manyuan, Wang Shiping

Primary Institution: National Key Laboratory of Crop Genetic Improvement, National Center of Plant Gene Research (Wuhan), Huazhong Agricultural University

Hypothesis

Can a new gene in rice evolve de novo to enhance disease resistance?

Conclusion

The study found that the OsDR10 gene negatively regulates rice's defense response to pathogens, and its suppression enhances resistance.

Supporting Evidence

  • OsDR10 suppression led to enhanced resistance against multiple strains of Xanthomonas oryzae.
  • Transgenic plants with suppressed OsDR10 showed significantly reduced lesion areas after pathogen infection.
  • Lower levels of OsDR10 transcripts were associated with increased disease resistance.

Takeaway

Scientists discovered a new gene in rice that helps the plant fight off diseases. When they turned off this gene, the rice plants became better at resisting infections.

Methodology

The researchers used RNA interference to suppress the OsDR10 gene in rice and analyzed the resulting disease resistance.

Participant Demographics

The study involved various rice lines, including both resistant and susceptible cultivars.

Statistical Information

P-Value

p<0.01

Statistical Significance

p<0.01

Digital Object Identifier (DOI)

10.1371/journal.pone.0004603

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